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Reimagine Mental Health

STANFORD CENTER FOR PRECISION MENTAL HEALTH

Our vision is for a precision approach to psychiatry in which neuroscience insights about the human brain are translated into real-world clinical care and to improve the quality of individual lives.

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STRATEGIC THEMES

Our three interconnected research themes span the path from understanding individual differences to personalizing treatment and improving outcomes. Across these themes, explainable human-centered AI, clinical decision support and real-world translation help move precision measurement from evidence to use. 

Define Individual Differences That Matter

Identify and measure biologically meaningful differences within and across traditional diagnoses. Integrate brain circuit, behavioral, clinical and other patient-level measures to understand heterogeneity at the level of the individual and determine which differences matter for prevention and treatment.

Personalize Treatment to Improve Outcomes

Use Personalized Circuit Scores and other precision measures to personalize treatment selection with the goal of improving outcomes. Our work spans medications, behavioral treatments and neuromodulation, moving beyond one-size-fits-all and prolonged trial-and-error care.

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Precision Stratification for New Therapeutics

Use Precision Circuit Mapping and biologically informed stratification to identify which individuals are most likely to benefit from new and emerging therapeutics, including mechanistically selective treatments, ketamine, MDMA-assisted therapy and psilocybin.

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